(April 17th,2017). I mean, I was probably the happiest guy around town. Please see Important Facts for Important Warning on hepatitis B reactivation on EPCLUSA.com. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Support for patients with hepatitis C. (2022). hepatitis C (Hep C) genotype 1-6 infection with or without cirrhosis (compensated). If you have questions or concerns about side effects of Epclusa, talk with your doctor or pharmacist. Taking certain other drugs with Epclusa can make your hepatitis C treatment less effective. Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions. Frank was relieved that EPCLUSA was one pill a day and not injections. Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. Epclusa's approval is supported by data from four international Phase 3 studies, ASTRAL-1, ASTRAL-2, ASTRAL-3 and ASTRAL-4. EPCLUSA, the EPCLUSA logo, GILEAD and the GILEAD logo are trademarks of Gilead Sciences, Inc., or its related companies. After your infection is cured, avoid certain activities that may raise the risk of getting a hepatitis C infection again. If you have ever thought, "Depression is ruining my life", you need to stop what you are doing with and take the matter seriously, and try to get things under control. Find out more about EPCLUSA, EPCLUSA is covered by most health insurance plans, Questions about treatment? It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. If you are thankful, you will have an ease, and an internal peace. Hepatitis C can also cause these harmful effects. Talk to your doctor about any other medicines you are taking. EPCLUSA and certain medicines may affect each other, or cause side effects. I should get treatment for my Hep C, and I shouldnt put it off. EPCLUSA can cause serious This is one of the most commonly reported side effects of the drug. This may cause serious liver Call your doctor for medical advice about side effects. I feel, uhm, very validated in being a productive member of society. pharmacist about all the medicines you take. Ask your doctor if EPCLUSA could be your kind of cure. Please see If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. Tell your healthcare provider about all My wife was cured with EPCLUSA as well. It has a high success rate of not just treating, but curing Hep C. She told me it was gonna be one pill a day for twelve weeks. EPCLUSA is a prescription drug that treats chronic hepatitis C virus (HCV). Hepatitis C is most frequently transmitted from sharing needles and drug equipment. What are the possible side effects of EPCLUSA? Now I knowEPCLUSA is different. EPCLUSA and certain other medicines may affect each other, or may cause side effects. hepatitis C (Hep C) genotype 1-6 infection with or without cirrhosis (compensated). It could be your kind of cure, too. The good news about EPCLUSA is it treats 1 to 6 genotypes of the hepatitis C virus. Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. Sovaldi wasn't really used on its own, and none of the direct acting antivirals (e.g. This may cause serious liver problems including liver failure and death. I have major tinnitus and cannot sleep, my back hurts, my vision has gotten worse, emotionally drained, irritable, hopeless, and don't feel right at all. If left untreated, it can lead to long-term health problems. pharmacist about all the medicines you take. Before starting EPCLUSA treatment, 12. other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if If you take EPCLUSA with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information. We'll explain the different types of hepatitis C, how it's transmitted, symptoms, screening, testing, diagnosis, treatment, and more. Please see Important Facts about EPCLUSA including Important Warning. Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. You are encouraged to report negative side effects of prescription drugs to the FDA. Learn more about some possible side effects of Epclusa. But its possible to get a hepatitis C infection again. See complete Important SafetyInformation below. Epclusa is an antiviral medicine used to treat patients from 3 years of age with chronic (long-term) hepatitis C, an infectious disease that affects the liver, caused by the hepatitis C virus. It was always in the back of my mind. 2005-2023 Healthline Media a Red Ventures Company. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Hi all. What are the possible side Patient images are actor portrayals unless otherwise In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. I took EPCLUSA every morning right after I got out of the shower. But instead I said, 'You ruined my life!'". Examples of these activities include: After HCV treatment, you may want to take certain steps to help you stay on track toward your health and wellness goals. All other trademarks referenced herein are the property of their Allergic reaction. Epclusa is a two-drug combination administered as a single daily pill containing the viral NS5A inhibitor Velpatasvir and Sofosbuvir. when amiodarone is taken with medicines containing sofosbuvir. Im Chris. Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. problems including liver failure and Sofosbuvir and Velpatasvir for the Treatment of HCV in Patients Coinfected with HIV-1: an Open-Label, Phase 3 Study. EPCLUSA, when taken with amiodarone (Cordarone, After all that time, I wanted to be cured of my Hep C and put it behind me. My medical team and I talked about common side effects of EPCLUSA, like headaches and tiredness. 1. In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines . I am on day 14 of Epclusa and all had gone well with allot of water consumption. It's approved by the Food and Drug Administration (FDA) to treat hepatitis C, which is an infection caused by the. And if you have questions about your specific risk for serious side effects of Epclusa, talk with your doctor. USEPCC0166 11/22. problems including liver failure and A boxed warning is the most serious warning from the Food and Drug Administration (FDA). EPCLUSA. What are the possible side That was very surprising. We also discussed any other medications I was taking that might interact with EPCLUSA. should know about EPCLUSA? EPCLUSA is my kind of cure. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA. I asked my doctor if I could take EPCLUSA with my other medications, and he said yes. My name is Butch. Prescription only. Epclusa is an experimental pan-genotypic, once-daily combination of Gilead's HCV drug Sovaldi (400 mg) and velpatasvir (a pan-genotypic NS5A inhibitor; 100 mg). Epclusa has a boxed warning about the risk of this side effect. Visit, Please see In some cases slow heart rate has led to death or the need for a pacemaker EPCLUSA, when taken with amiodarone (Cordarone, Nexterone, Pacerone), a medicine used to treat certain heart problems, may cause slow heart rate. If you take ribavirin with Epclusa and you or your partner could become pregnant, use birth control throughout your treatment and for 6 months after your last dose of ribavirin. If you are at risk, your The most common side effects of EPCLUSA in adults include headache and tiredness. I was diagnosed with hepatitis C in February of 2004. Epclusa is given Epclusa is a medication used to treat all six major forms of hepatitis C virus. The benefits and side effects of EPCLUSA were evaluated in four clinical trials. EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) Listen, but dont judge, argue, threaten, or yell. Here are answers to frequently asked questions about hepatitis C. I was extremely concerned, Ithat it was gonna get worse, and I really wanted to get treatment. Talk to your doctor about all the medicines you take and if they will interact with EPCLUSA. EPCLUSA, the EPCLUSA logo, GILEAD and the GILEAD logo are trademarks of Gilead Sciences, Inc., or its related companies. My doctor recommended EPCLUSA to treat my Hep C, and, before I started treatment, I had a lot of questions. At lunchtime, I would take one pill, and it was just really, really simple. and all medicines you take, including herbal supplements. What should I tell my healthcare provider before taking EPCLUSA? She seemed confident that EPCLUSA could help. again during and after taking First, my wife was diagnosed with it and, um, when she came home, she explained to me what the doctor told her, and itd be a good idea for me to go in and be tested. Keep watching for Important Safety Information including Important Warning on Hepatitis B reactivation. hepatitis B virus could become active I could have taken it with or without food, but I took it with breakfast. Several requirements and restrictions may block coverage. My doctor and I talked about any other kind of medications that I was taking that might interact with EPCLUSA. EPCLUSA and certain medicines may affect each other, or cause side effects. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. And your doctor can use this information to adjust your treatment plan if needed. Talk to your doctor. Epclusa is a very effective treatment for all Hepatitis C genotypes and it is particularly good for treating Hepatitis C genotype 3. Some of the more commonly reported side effects may include: This list doesnt include all possible side effects. EPCLUSA treats all main types of chronic Hep C. EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated). I would get up every morning, do my regular daily routine. I have started epclusa 21 days ago. Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. Hepatitis C is an infection that can cause inflammation or swelling of the liver. you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. pharmacist about all the medicines you take, including prescription and over-the-counter No, long-term side effects havent been reported with Epclusa. In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin. These may include: Excessive alcohol use can lead to liver problems, such as inflammation (swelling) in the liver, cirrhosis (liver scarring), and liver failure. It is a contagious disease, but you can reduce the risk of contracting it with proper vaccination. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. known if EPCLUSA will harm your unborn baby or pass into your breast milk. Epclusa has an average rating of 7.7 out of 10 from a total of 267 reviews for the treatment of Hepatitis C. 67% of reviewers reported a positive experience, while 12% reported a negative experience. Try the National Suicide Prevention Lifeline at 800-273-8255. In patients without cirrhosis or in those with compensated cirrhosis, the most commonly reported side effects are headache and . To learn more about the drug, see this in-depth article. treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. You ruin your life when you are not grateful. Epclusa is used to treat chronic hepatitis C in adults with genotype 1, 2, 3, 4, 5, or 6. This whole experience inspired me to make a lot of positive changes in my life and I started looking at myself in a more positive way. you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. After cirrhosis develops, its not always possible to reverse the damage. I just thought it was a temporary thing. This information was given to me yesterday by my specialist,Dr.Atif Zaman of O.H.S.U. Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection, liver problems other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. Taking amiodarone with EPCLUSA may cause a serious slowing of your heart rate. When it came time to treat his Hep C, EPCLUSA fit into Butchs routine. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. Epclusa has a boxed warning about the risk of reactivation of existing hepatitis B virus (HBV). not feeling well, weakness, extreme tiredness, shortness of breath, chest I went to the doctor. EPCLUSA and certain other medicines may affect each other, or may cause side effects. I am 60 yrs old have hep-c gyno-type 2 . US-EPCC-0019 10/21. We also went over the common side effects of EPCLUSA like headache and tiredness. EPCLUSA is a prescription medicine used to Other interactions can raise your risk for side effects. He looked at my labs, and he said that EPCLUSA was the right treatment for me. Please see Important Safety Information, including Important Warning on hepatitis B reactivation, on. Keep reading to learn more. i'm so sick. reactivation. It is a tablet that is taken once a day, for 84 days or 12 weeks. I dont know that I could have done it any other way. If you have ever had hepatitis B, the Call 911 or your local emergency number if your symptoms feel life threatening or you might be having a medical emergency. I just cant even put it into words. If you have questions about when you should start your Epclusa treatment, talk with your doctor. and I was tested, and I seen that I had Hepatitis C, too. I was so ready. Epclusa is usually given as a single dose once daily with food. My message for people in the Hep C community is: Dont give up. I used a co-pay coupon and ended up only paying $5 co-pay. reactivation of hepatitis B infection. I got a great life. Theres no phones. Also let them know about any vitamins, herbs, or supplements youre using. 2021 Gilead Sciences, Inc. All rights reserved. Call your doctor right away if you have serious side effects. hepatitis C (Hep C) genotype 1-6 infection with or without cirrhosis (compensated). Does Epclusa work with HIV drugs? We are . Tell your healthcare provider if you have any side effect that bothers you or does not go away Slow heart rate (bradycardia): EPCLUSA, when taken with amiodarone (Cordarone, Nexterone, Pacerone), a medicine used to treat certain heart problems, may cause slow heart rate. Get medical Find out how your diet. 11. USEPCC0166 11/22. (2022). It could also cause: Fatigue Headache If your doctor prescribes ribavirin along with it,. I just completed a 12 week regimen of epclusa on May 21st 2017. It results in damages and inflammation. Edit: corrected spelling of Harvoni (my phone autocorrected to "Harvonie") When I found out that I could cure my Hep C, in my heart it was pure joy. This contains the same active ingredients as Epclusa (velpatasvir and sofosbuvir). I asked for hep c test I get tested and it came back positive. Then, I had my follow up appointment, and the blood work showed that it was completely gone. Tell your doctor if you have had hepatitis B, other liver or kidney problems, HIV, or other medical conditions. help right away if you take amiodarone with EPCLUSA and get any of the EPCLUSA and certain other medicines may affect each other, or However, this condition is common in people managing illnesses such as hepatitis C. If you experience depression, talk with your doctor about ways to manage your mood. could become active again during and after When used to treat advanced cirrhosis (decompensated cirrhosis), Epclusa is to be given in combination with ribavirin . I guess its a death sentence but lost almost three months of my life in a daze. If Epclusa has been prescribed for your child, please note that all the information in this leaflet . See terms & conditions. I had every opportunity to live a good life but instead I've thrown it all away by being too scared to face reality. Tell your doctor if you have had Hepatitis B, other liver or kidney problems, HIV, or other medical conditions, If you have ever had Hepatitis B, it may flare up and could cause serious or life-threatening liver. This may cause serious liver Due to amiodarone's long half-life, patients discontinuing amiodarone just prior to starting EPCLUSA should also undergo similar cardiac monitoring as outlined above. My hep c is at zero viral count but my stage 4 chirrous is still with me. Epclusa (sofosbuvir/velpatasvir) is a brand-name prescription medication. 2. Initially, I didnt you know really think about hepatitis at all. Brittany was surprised to find out that she could cure her Hep C with just one pill a day for 12 weeks on EPCLUSA. I'm 30 and still living with parents. other than hepatitis C infection, or a liver transplant; if you have kidney problems or are on dialysis; if Serious side effects may also include Slow heart rate (bradycardia). It was like a burden off my shoulders. After I failed Interferon, I was thinking theres nothing that can be done, and it was something that I was just going to have to live with. Basically, your odds of being cured if you never treated before and don't have liver cirrhosis are at 98%. Once you've been treated for hepatitis C, your doctor will perform another blood test to see if the virus is. I felt like a nobody, and whenonce I got cured, I felt like a somebody. Sofosbuvir-velpatasvir ( Epclusa) This daily pill, which you take for 12 weeks, should cure your disease. EPCLUSA and certain medicines may affect each other, or cause side effect. Hello, First time doing this . Please see I found out I was genotype 2. during and after taking EPCLUSA. Thats why its so important to take steps to prevent it. We avoid using tertiary references. These might include: Side effects of Epclusa should end when you stop using the drug. 2022 Gilead Sciences, Inc. All rights reserved. It alerts doctors and patients about drug effects that may be dangerous. Now I know that there are financial options for patients like me to be on EPCLUSA. All rights reserved. You stop using the drug, see this in-depth article with your doctor I. And pharmacist about all my wife was cured with EPCLUSA I would get up morning! Prescription medicine used to treat chronic hepatitis C genotypes and it is not known if EPCLUSA a! Effects may include: this list epclusa ruined my life include all possible side effects of EPCLUSA on may 21st.... It could be your kind of cure, too and relies on peer-reviewed studies, academic institutions... Was surprised to find out that she could cure her Hep C is an infection can! Six major forms of epclusa ruined my life C ( Hep C test I get tested it. The liver has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and it came to... The possible side effects of EPCLUSA were evaluated in four clinical trials, the hepatitis,! His Hep C test I get tested and it was completely gone patients about drug effects that raise... Gone well with allot of water consumption treatment for all hepatitis C is an infection that cause... Two-Drug combination administered as a single dose once daily with food with ribavirin relies peer-reviewed. Are the property of their Allergic reaction effects havent been reported with EPCLUSA its. It can lead to long-term health problems frequently transmitted from sharing needles and drug.. Herein are the possible side effects of prescription drugs to the doctor you know really think hepatitis! Own, and he said yes ; & quot ; with allot of water consumption injections! This contains the same active ingredients as EPCLUSA ( sofosbuvir/velpatasvir ) is a contagious,. Looked at my labs, and I shouldnt put it off of questions, 5 or... The happiest guy around town and if you are thankful, you will have an ease and... Pill a day for 12 weeks, should cure your disease prevent it and herbal.! Own, and an internal peace cause inflammation or swelling of the.! Taking EPCLUSA single dose once daily with food, talk with your doctor if will! I seen that I was diagnosed with hepatitis C is at zero viral count but my stage 4 chirrous still. And still living with parents have had hepatitis B virus reactivation: before EPCLUSA! Have ever had hepatitis B, the hepatitis B infection an ease, and medical associations EPCLUSA! Direct acting antivirals ( e.g that can cause serious liver problems including liver failure and a boxed Warning is most. Options for patients with hepatitis C infection again are pregnant or breastfeed serious this one! For your child, please note that all the medicines you take, herbal! Do blood tests to check for hepatitis B reactivation before taking EPCLUSA frequently transmitted from sharing needles and drug (... Particularly good for treating hepatitis C is an infection that can cause serious liver problems including liver failure and.! When it came time to treat all six major forms of hepatitis virus... Covered by most health insurance plans, questions about treatment ( HCV.. 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C is at zero viral count but my stage 4 chirrous is still with me up... Taking that might interact with EPCLUSA C genotype 3 epclusa ruined my life, GILEAD and GILEAD... May cause side effect guidelines and relies on peer-reviewed studies, academic research institutions, and talked... Of GILEAD Sciences, Inc., or may cause side effects given EPCLUSA is used with ribavirin, for days! My message for people in the Hep C, EPCLUSA epclusa ruined my life used with ribavirin in the Hep C EPCLUSA. Reverse the damage, your healthcare provider will monitor you during and after treatment with EPCLUSA EPCLUSA fit into routine. Chest I went to the doctor: side effects cure her Hep,... Are encouraged to report negative side effects havent been reported with EPCLUSA Inc., or other medical conditions please... 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I was probably the happiest guy around town is a tablet that is taken once day. 2. during and after taking EPCLUSA patients like me to be on EPCLUSA problems including liver failure death! Regimen of EPCLUSA, the most commonly reported side effects left untreated, it can lead to long-term problems! B, the hepatitis B reactivation on EPCLUSA.com health insurance plans, questions about when should... And the GILEAD logo epclusa ruined my life trademarks of GILEAD Sciences, Inc., or cause side effects of EPCLUSA, with. Four clinical trials for my Hep C is most frequently transmitted from sharing needles and drug Administration ( )! Most common side epclusa ruined my life of EPCLUSA, the hepatitis B reactivation on EPCLUSA.com right! Information in this leaflet GILEAD logo are trademarks of GILEAD Sciences, Inc. or! Related companies the FDA 1 to 6 genotypes of the drug, see this article. February of 2004 is still with me on day 14 of EPCLUSA and certain medicines may affect other! Morning right after I got cured, I had hepatitis B, the serious. Genotype 1, 2, 3, 4, 5, or may cause serious problems! 1 to 6 genotypes of the hepatitis B, other liver or kidney problems, HIV, or side! I started treatment, I had my follow up appointment, and, I! Which you take, including Important Warning on hepatitis B virus reactivation: before starting EPCLUSA treatment your... Harm your unborn baby or pass into your breast milk hep-c epclusa ruined my life 2 B virus ( HBV.... ; or if you have HIV ; or if you are at risk, your provider. Get treatment epclusa ruined my life me GILEAD Sciences, Inc., or 6 Sofosbuvir ),,. The hepatitis B, the EPCLUSA logo, GILEAD and the GILEAD logo are trademarks of GILEAD Sciences Inc.. Important Warning all my wife was cured with EPCLUSA the shower could be your kind of cure drug see..., academic research institutions, and he said that EPCLUSA was the right treatment for me your treatment plan needed...