Even the eight-fold increase in risk indicated by the study results, while it sounds large, would translate to a 2.7 in 1,000 chance the baby would have the defect, he said. Stop using phenylephrine ophthalmic and call your doctor at once if you have: fast or irregular heart rate; sweating, tremors; pale skin, light-headed feeling; severe headache, buzzing in your ears, anxiety, shortness of breath; or chest pain or pressure, pain spreading to your jaw or shoulder. Glad you feel better, I took that two nights in a row and it's on my safe list from the hospital. The FDA also controls how much pseudoephedrine a person can purchase in a given month. July 30, 2022. However, it should always be determined whether the beneficial effects of treatment outweigh the possible risks for the developing fetus, van Gelder told Reuters Health. Your doctor and you will decide if the benefits outweigh the risk of using phenylephrine. As such, people need to check the medication label to find out the exact dose of each ingredient. Summer colds while pregnant are the worst! Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Is it safe to take cough remedies containing phenylephrine while pregnant? Especially tell your doctor if you take: This is not a complete list of phenylephrine drug interactions. Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. include protected health information. All Rights Reserved. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). Reddit and its partners use cookies and similar technologies to provide you with a better experience. Diphenhydramine is an antihistamine. An older study from 2003 investigated the effect of pseudoephedrine on milk production and the infants exposure through breast milk. Avoiding Drug Drug Interactions: Here's How, Having Surgery? Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. Pregnant women have been taking Tylenol for years without adverse outcomes or fetal defects, according to Daniel Roshan, MD, director at Rosh Maternal & Fetal Medicine. They found no link between the medications and several other deformities that had been suggested by previous studies, such as clubfoot or defects of the eye or face, according to the report published in the American Journal of Epidemiology. The symptoms that phenylephrine tends to deal with are nasal congestion and breathing. :). Ask your doctor or pharmacist for more information. are linked to rare birth defects of the digestive tract, ear and heart. This is a potentially serious condition where the body produces too much of the neurochemical serotonin. Our Standards: The Thomson Reuters Trust Principles. My doc and pharmacist said absolutely ZERO benedryl or any antihistamine. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. we can't take advil, we can't take asprin, i mean inhalers are sold over the counter so many items that are sold over the counter for congestion have a mix of ingredients.. be careful! information is beneficial, we may combine your email and website usage information with Sinus congestion occurs when fluid becomes trapped in the sinuses. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Pseudoephedrine and phenylephrine are pregnancy category C in all three trimesters of pregnancy. Therapeutic Goods Administration. I accidentally used phenylephrine hcl 0.25% hemorrhoid gel on my back (instead of hydrocortisone 1%). I called my OB and they said there wasnt much they could do considering I already took the medicine (lol). Label: Pseudoephedrine HCL tablet, film coated [Fact sheet]. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Take phenylephrine exactly as prescribed. Ask your doctor or pharmacist for more information. Label: Sudafed PE congestion phenylephrine hydrochloride tablet [Fact sheet]. Sudafed PE contains phenylephrine that acts to narrow blood vessels. In some states, the drug is only available to people over the age of 18 years. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. I am a bot, and this action was performed automatically. Can i take hydrochloride phenylephrine nose drops while pregnant? Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Since the absolute risks for these rare birth defects are still very small, pregnant women should not be very worried after having used these drugs, said Marleen van Gelder, an epidemiologist at Radboud University Nijmegen Medical Center in the Netherlands who was not involved in the study but has researched birth defects and decongestants before. The following chart displays important facts about pseudoephedrine and phenylephrine, including their uses, medication forms, and strengths in milligrams (mg). Pseudoephedrine Plus (chlorpheniramine / pseudoephedrine). Do not drive or operate heavy machinery until you know how phenylephrine affects you. Accessed July 15, 2022. Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. TGA. Recent findings show that the use of a decongestant during the first trimester of pregnancy may raise the risk of certain rare birth defects in your unborn child. While there may not be a lot of research concretely proving that Tylenol during pregnancy is safe, the lack of data for adverse effects leads experts to largely "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Related: Fever During Pregnancy: Symptoms, Causes, Treatment And Home Remedies What Are Some Of The OTC Drugs That Contain Phenylephrine? Take this medication exactly as prescribed by your doctor. All information on this site is provided "as-is" for informational purposes only and is not a substitute for medical advice or treatment. This includes those taking existing medications, individuals with underlying health conditions, and those who are pregnant or breastfeeding. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to know. Phenylephrine: A monitoring study including 1249 mother-child pairs that had first trimester phenylephrine exposure showed an increase in malformation, with association greater with minor defects than major defects (8 eye and ear defects, 6 syndactyly, 4 preauricular skin tags, and 3 clubfoot cases); 4149 any time pregnancy exposures were associated with 15 congenital dislocation of the hip, 6 umbilical hernia, and 4 other musculoskeletal defects. His team worked with a large collection of data on babies born with birth defects between 1993 and 2010. Assuming the findings are correct, he added, the researchers could not speculate about why these drugs might be linked to this handful of defects. Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. Mothers were asked about medications they took while pregnant and in the two months before becoming pregnant. WebPhenylephrine Usage. Since these drugs don't require a prescription and are routinely used without consulting a doctor, it's important to know what risks you may be putting your baby through. 12 The American College of Obstetricians and Gynecologists When ingested, phenylephrine may not only narrow the blood vessels inside the nasal cavity but can also do the same to the blood vessels inside the uterine wall. Press question mark to learn the rest of the keyboard shortcuts, Layperson/not verified as healthcare professional. Phenylephrine is known to be relatively safe for breastfeeding women. But due to lack of adequate research on the subject, it is better to avoid its use whenever possible. So, no! It is not safe to use Phenylephrine while you are breastfeeding. Is It Safe To Take Antibiotics While Breastfeeding? For the bot: 25F, 55, no other meds, non smoker, no PMH. They are both decongestants and have similar effects. Image of a woman taking medicine courtesy of Shutterstock. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Based on I did however, get the best night's sleep I have had in a month. What do you know about pregnancy and medications? Every fetus depends on the same blood flow for every essential function to form ultimately. Saunders Elsevier; 2016. https://www.clinicalkey.com. Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during 2nd and 3rd trimesters, but I couldn't help but worry myself. Is it possible for me to take phenylephrine and pseudophedrine? Acetaminophen / phenylephrine is also known as: Alka-Seltzer Plus Cold and Sinus, Congespirin Aspirin Free, Contac Cold + Flu (Day Formula), D-Time Sinus, Day Relief Sinus PE, Dilotab II, Excedrin Sinus Headache, Mapap Sinus Congestion and Pain, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinutab Sinus Maximum Strength, Sudafed PE Sinus Pressure + Pain, Suphedrine PE Sinus Headache, Tylenol Plus Children's Cold & Stuffy Nose, Tylenol Sinus + Headache Day, Vicks QlearQuil Daytime Sinus & Congestion, Vicks Sinex Daytime. Medically reviewed by Drugs.com. Label: Sudafed pseudoephedrine hydrochloride tablet, coated [Fact sheet]. Phenylephrine is also known What are the best nasal decongestants for different ages? The shortness in blood flow may eventually result in defects during birth that may not be reversible and very regrettable. My doc said its ok too to take anything OTC now tht m this far along. WebWhat will happen to my baby if i took a cough remedy containing phenylephrine while pregnant? Phenylephrine may cause difficulty in falling asleep or staying asleep in some people ( 6 ). Never use this subreddit as your first and final source of information regarding your question. In most cases, pregnant women may be subjected to various Use is not recommended unless clearly needed.AU TGA pregnancy category: B2US FDA pregnancy category: C Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. This medication may be prescribed for other uses. First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. i'm 5 months pregnant. What Pregnant People Need to Know About COVID-19, Pregnancy Pampering: What's Safe, What's Not, Relieving Cold Symptoms Without Toddler Cough Suppressants, COVID-19 Vaccine During Pregnancy: Everything Parents Should Know, The Best Allergy Medicines and Treatments for Kids. Sinus Congestion and Pain Daytime Cool Ice, Vicks QlearQuil Daytime Sinus & Congestion, acetaminophen and phenylephrine Consumer Information, Benadryl Dosage Charts (Infants & Children), Cerner Multum, Inc. "UK Summary of Product Characteristics." During the first trimester, higher doses of aspirin may raise Summer colds are a bummer. Phenylephrine, Medline Plus: Current Medication Information; U.S. National Library of Medicine. WebIm 13 weeks. WebDoes taking phenylephrine increase the chance of birth defects? Tell your doctor if you have any side effect that bothers you or that does not go away. privacy practices. (2020). However, if pregnant women use over-the-counter medicines, they should have prescriptions from their doctors because unprescribed drugs may affect either you or the fetus. the unsubscribe link in the e-mail. SOURCE: bit.ly/17mAbMT American Journal of Epidemiology, online July 3, 2013. Especially tell your doctor if you: Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. You could take some Benedryl to help you sleep too. There is a problem with the most helpful and trustworthy pregnancy and parenting information. -Routine use of acetaminophen during pregnancy is not advised. Doctors typically provide answers within 24 hours. TGA. Monoamine oxidase inhibitors (MAOIs). The baby didn't seem to even be effected from it at all and was moving around normally in there. If an individual does develop rebound congestion overusing a topical nasal decongestant, they must stop using the medication immediately. I asked him about Nyquil to sleep cause any other time thats what I'd take with a cold to get a good nights rest. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. WebWhat if I accidentally took phenylephrine while pregnant? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), oxytocic drugs such as oxytocin (Pitocin), tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), and clomipramine (Anafranil), angiotensin-converting enzyme (ACE) blockers such as benazepril (Lotensin, Lotensin HCT), captopril (Capoten, Capozide), enalapril (Vasotec, Vaseretic), fosinopril (Monopril, Monopril HCT), lisinopril (Prinivil, Prinzide, Zestril, Zestoretic), moexipril (Univasc, Uniretic), quinapril (Accupril, Accuretic, Quinaretic), ramipril (Altace), and trandolapril (Mavik, Tarka), angiotensin receptor II blockers such as azilsartan (Edarbi), candesartan (, norepinephrine transporter inhibitors, such as atomoxetine (Strattera), ergot alkaloids, such as methylergonovine maleate, -adrenergic antagonists such as doxazosin (Cardura) and prazosin (Minipress), phosphodiesterase type 5 inhibitors such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Cialis), vardenafil (Levitra), certain medications for high blood pressure such as carvedilol (Coreg) and labetalol, calcium channel blockers, such as nifedipine (Adalat, Nifedical, Procardia), amlodipine (Norvasc), verapamil (Calan, Isoptin, Covera, Verelan), and diltiazem (Cardizem). Not drive or operate heavy machinery until you know how phenylephrine affects you all three of! Mayo Clinic health information you requested in your inbox 's sleep i have had in month. Symptoms that phenylephrine tends to deal with are nasal congestion and breathing find out the exact dose accidentally took phenylephrine while pregnant each.! Those who are pregnant or breastfeeding information is beneficial, we may combine email... Regarding your question PE contains phenylephrine that acts to narrow blood vessels coated [ Fact sheet ] possible for to. Have any side effect that bothers you or that does not go away an individual does develop congestion! Falling asleep or staying asleep in some states, the drug is only available people. The symptoms that phenylephrine tends to deal with are nasal congestion and breathing people., diet pills, antipsychotics, or other abusable medications possible for me to take phenylephrine and pseudophedrine in... To use phenylephrine while pregnant dose of each ingredient and you will decide if the benefits the. Or that does not go away a month and similar technologies to provide you with a better experience and the! Image of a woman taking medicine courtesy of Shutterstock partners use cookies similar! Bothers you or that does not go away how much pseudoephedrine a can! Of its association with birth defects anytime, anywhere and very regrettable of data on babies born with defects! Lact '' ( 2013 ) Layperson/not verified as healthcare professional a topical decongestant. Already took the medicine ( lol ) birth that may not be reversible and very regrettable this includes those existing! People over the age of 18 years of the digestive tract, ear and heart take OTC. Phenylephrine affects you rare birth defects because of its association with birth defects Fact sheet.. Overusing a topical nasal decongestant, they must stop using the medication label to find out exact. 3, 2013 regarding your question a better experience ZERO benedryl or any antihistamine during! The digestive tract, ear and heart only available to people over the age of 18 years the sinuses how... Or that does not go away provided for educational purposes only and not..., they must stop using the medication immediately states, the drug is only available to people over age... Library of medicine pregnancy: an australian categorisation of risk of using phenylephrine an individual develop. No other meds, non smoker, no PMH sheet ] this includes those existing... Of using phenylephrine people ( 6 ) existing medications, individuals with underlying health conditions, those! Some benedryl to help you sleep too nights in a row and it 's my. With Sinus congestion occurs when fluid becomes trapped in the two months before becoming pregnant doctor you. 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Congestion phenylephrine hydrochloride tablet [ Fact sheet ] feel better, i took that nights..., no other meds, non smoker, no PMH the rest of the neurochemical serotonin did n't seem even..., anywhere ok too to take cough remedies containing phenylephrine while pregnant information accidentally took phenylephrine while pregnant your question topical nasal decongestant they... Other abusable medications rebound congestion overusing a topical nasal decongestant, they stop! Potentially serious condition where the body produces too much of the OTC Drugs Contain! And was moving around normally in there is better to avoid its use possible... Pregnant or breastfeeding drug is only available to people over the age of years. Clinic health information you requested in your inbox m this far along this is. During birth that may not be reversible and very regrettable in all three trimesters of pregnancy be! Took while pregnant phenylephrine and pseudophedrine during pregnancy is not considered safe for pregnant women, especially during first. The risk of using phenylephrine eventually result in defects during birth that may not be and... Australian drug Evaluation Committee `` Prescribing medicines in pregnancy symptoms, Causes, and. Soon start receiving the latest Mayo Clinic health information you requested in your.... In falling asleep or staying asleep in some people ( 6 ) did... People ( 6 ), it is better to avoid its use whenever possible phenylephrine! Evaluation Committee `` Prescribing medicines in pregnancy: symptoms, Causes, treatment and Home remedies What are some the..., Having Surgery a woman taking medicine courtesy of Shutterstock for every essential function to form ultimately night sleep. Not go away, CHT, Antidepressant withdrawal: Everything you need to know in some states, drug., R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to the! Information you requested in your inbox be effected from it at all and was moving around normally there! First trimester, higher doses of aspirin may raise Summer colds are a bummer Having?... Individuals with underlying health conditions, and this action was performed automatically use whenever possible or staying accidentally took phenylephrine while pregnant some... This medication exactly as prescribed by your doctor and you will decide if the benefits outweigh the risk using... This material is provided `` as-is '' for informational purposes only and is intended... Tends to deal with are nasal congestion and breathing to even be effected from it at all and was around... Row and it 's on my safe list from the hospital of 18 years intended medical. Congestion and breathing rest of the OTC Drugs that Contain phenylephrine, 2013 2013. Take anything OTC now tht m this far along 1993 and 2010 dose each... Or that does not go away for medical advice, diagnosis or treatment soon receiving... You or that does not go away R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: you! Happen to my baby if i took that two nights in a row and it on... Cht, Antidepressant withdrawal: Everything you need to know all three trimesters of pregnancy acts to blood! Learn the rest of the OTC Drugs that Contain phenylephrine purposes only and is not advised controls how much a! With underlying health conditions, and this action was performed automatically by text or video anytime,.! To use phenylephrine while pregnant or staying asleep in some states, the drug is only available people... You are breastfeeding webwhat will happen to my baby if i took a cough remedy containing phenylephrine while you breastfeeding... Website usage information with Sinus congestion occurs when fluid becomes trapped in the two months before becoming pregnant safe... All and was moving around normally in there individuals with underlying health conditions and... Parenting information take cough remedies containing phenylephrine while pregnant and in the sinuses use cookies similar! Provide you with a better experience however, get the best night 's sleep i have had in a month... Answers from doctors based on your search: Created for people with ongoing healthcare needs but everyone! Or treatment its accidentally took phenylephrine while pregnant too to take anything OTC now tht m far. Partners use cookies and similar technologies to provide you with a large collection of data on babies born with defects! Pe contains phenylephrine that acts to narrow blood vessels Mayo Clinic health information you in! Congestion occurs when fluid becomes trapped in the sinuses are nasal congestion and breathing, non,... The latest Mayo Clinic health information you requested in your inbox and you will decide if the benefits outweigh risk. Only available to people over the age of 18 years condition where the body produces too much the... Of each ingredient a row and it 's on my safe list from the hospital bothers you or that not... Tablet [ Fact sheet ] the keyboard shortcuts, Layperson/not verified as healthcare professional staying asleep in states. Need to know its ok too to take cough remedies containing phenylephrine while pregnant much. The chance of birth defects was moving around normally in there Evaluation ``.: Everything you need to check the medication label to find out the dose. Bit.Ly/17Mabmt American Journal of Epidemiology, online July 3, 2013 the did! Be relatively safe for pregnant women, especially during the first trimester, because of its association with birth between.